SFB 1309
Exact distance measurements for structure and dynamics in solid proteins by fast-magic anglespinning NMR†
2019-06-05
Kristof Grohe, Evgeny Nimerovsky, Himanshu Singh, Suresh K. Vasa, Benedikt Söldner, Beat Vögeli, Chad M. Rienstra, Rasmus Linser
Chem. Commun., 2019, 55, 7899
Fast-magic-angle-spinning solid-state NMR is a developing technique for determination of protein structure and dynamics. Proton–proton correlations usually lead to rough distance restraints, a serious hurdle towards high-resolution structures. Analogous to the “eNOE” concept in solution, an integrative approach for more accurate restraints enables improved structural accuracy with minimal analytical effort.
